Pentobarbital will decrease the level or effect of budesonide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of zonisamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of saxagliptin by affecting hepatic/intestinal enz... https://bookmarkedblog.com/story21228492/la-regola-2-minute-per-protocollo-eutanasia-animale-con-pentobarbital