Preliminary reports reveal conolidine may perhaps inhibit specific ion channels, lowering neuronal excitability and limiting agony signals. This mechanism is particularly appropriate in neuropathic agony, wherever abnormal signaling results in persistent discomfort. Furthermore, conolidine appears to affect G protein-coupled receptor (GPCR) pathways integral to discomfort perception. ... https://timocid814ebx3.thebindingwiki.com/user