rifampin will minimize the level or effect of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified. Dose changes of such drugs and various medications which can be substrates for CYP2C19 might be important if modafinil is coadministered Keep track of Carefully (one)mitotane decreases amounts of modafinil by affecting https://modafinil71234.angelinsblog.com/25878396/modafinil-an-overview